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SYLLABUS – 1508 – BIOCHEMISTRY
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1508 – Biochemistry

UNIT 1 – BIOMOLECULES AND THE CELL
Major complex biomolecules of cell and cell organelles-Prokaryotic and eukaryotic cell
UNIT 2 – CARBOHYDRATES
Chemical structure, function- Classification- Monosaccharides- Disaccharides-
Polysaccharides-Homopolysaccharides-Heteropolysaccharides-Glycoproteins
UNIT 3 – PROTEINS
Amino acids- Classification- Structure of proteins- Determination of protein structure- Properties of proteins- Denaturation- Classification of proteins- Antigen, Antibody- Types, Plasma proteins- Blood clotting.
UNIT 4 – LIPIDS
Chemical structure, functions, Classification-fatty acids, Triacylglycerols, Phospholipids,glycoproteins, Lipoproteins- Steroids – Amphipathic lipids.
UNIT 5 – NUCLEIC ACIDS
Purines and pyrimidine- Structure of DNA – Watson & Crick model of DNA – Structure of RNA – Types of RNA
UNIT 6 – ENZYMES
Definition – Nomenclature – Classification – Factors affecting enzyme activity – Active site – Coenzyme – Enzyme Inhibition – Mechanism of enzyme action – Units of enzyme – Isoeznzymes – Enzyme pattern in diseases.
UNIT 7 – VITAMINS & MINERALS
Fat soluble vitamins (A,D,E,K) – Water soluble vitamins – B-complex vitamins- principle elements (Calcium, Phosphorus, Magnesium, Sodium, Potassium, Chlorine and Sulphur) – Trace elements – Calorific value of foods – Basal metabolic rate (BMR) – respiratory quotient (RQ) Specific dynamic action (SDA) – Balanced diet – Marasmus – Kwashiorkor
UNIT 8 – HORMONES
Classification – Mechanism of action – Hypothalamic hormones – Pituitary – Anterior, posterior – Thyroid – Adrenal cortex, Adrenal medulla – Gonadal hormones – Menstrual cycle – GI hormones
UNIT 9 – ACIDS AND BASES

Definition, pH, Henderson – Hasselbalch equation, Buffers, Indicators, Normality,
Molarity, Molality, fluid and electrolyte balance.

약쨖 REFERENCE BOOKS

  1. Harper’s Illustrated Biochemistry: Victor W. Rodwell, David A. Bender, Kathleen M. Botham, Peter J. Kennelly, 32nd Edition.
  2. Lehninger Principles of Biochemistry: David L. Nelson, Michael M. Cox, 8th Edition.
  3. Lippincott Illustrated Reviews: Biochemistry ൓ Richard A. Harvey, Denise R. Ferrier, 8th Edition.

약쨚 TEXTBOOKS

  1. Textbook of Biochemistry for Medical Students: D. M. Vasudevan, S. Sreekumari, Kannan Vaidyanathan,11th Edition.
  2. Biochemistry: U. Satyanarayana, U. Chakrapani, 7th Edition.
  3. Textbook of Medical Biochemistry: Dinesh Puri, 5th Edition.
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