Unit-I 10 Hours
Controlled drug delivery systems: Introduction, terminology/definitions and rationale, advantages, disadvantages, selection of drug candidates. Approaches to design controlled
release formulations based on diffusion, dissolution and ion exchange principles. Physicochemical and biological properties of drugs relevant to controlled release
formulations
Polymers: Introduction, classification, properties, advantages and application of
polymers in formulation of controlled release drug delivery systems.
Unit-II 10 Hours
Microencapsulation: Definition, advantages and disadvantages, microspheres
/microcapsules, microparticles, methods of microencapsulation, applications
Mucosal Drug Delivery system: Introduction, Principles of bioadhesion /
mucoadhesion, concepts, advantages and disadvantages, transmucosal permeability and
formulation considerations of buccal delivery systems
Implantable Drug Delivery Systems: Introduction, advantages and disadvantages,
concept of implants and osmotic pump
Unit-III 10 Hours
Transdermal Drug Delivery Systems: Introduction, Permeation through skin, factors
affecting permeation, permeation enhancers, basic components of TDDS, formulation approaches
: Introduction, advantages, disadvantages, approaches for GRDDS ᎓ Floating, high density systems, inflatable and gastroadhesive
systems and their applications
Nasopulmonary drug delivery system: Introduction to Nasal and Pulmonary routes of
drug delivery, Formulation of Inhalers (dry powder and metered dose), nasal sprays,
nebulizers

Unit-IV 08 Hours

Targeted drug Delivery: Concepts and approaches advantages and disadvantages,
introduction to liposomes, niosomes, nanoparticles, monoclonal antibodies and their
applications
Unit-V 07 Hours
Ocular Drug Delivery Systems: Introduction, intra ocular barriers and methods to
overcome ᎓Preliminary study, ocular formulations and ocuserts
Intrauterine Drug Delivery Systems: Introduction, advantages and disadvantages,
development of intra uterine devices (IUDs) and applications