Dear Students the Youtube Video has been uploaded for the following topics:Unit IUnit IIUnit IIIUnit IVUNIT V
Assignment topic is Unit IV and due date is 13-09-2025.
Assignment topic is UNIT V and due date is 15-09-2025.
Dear Students the Resource Link has been uploaded for the following topics:Introduction to Medicinal ChemistryPenicillin
Dear Students the Puzzles has been uploaded for the following topics:Hydrogen bonding, Protein binding,, Full
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Dear Students the Lecture Notes has been uploaded for the following topics:Introduction to Medicinal Chemistry, History and development of medicinal chemistry, Ionization, Solubility, Partition Coefficient,, Hydrogen bonding, Protein binding,, Chelation, Bioisosterism, Optical and Geometrical isomerism., Drug metabolism principles- Phase I, Drug metabolism principles- Phase II, Factors affecting drug metabolism including stereo chemical aspects. UNIT- II 1, Adrenergic Neurotransmitters: Biosynthesis and catabolism of catecholamine., Cholinergic neurotransmitters: Biosynthesis and catabolism of acetylcholine., Cholinergic receptors (Muscarinic & Nicotinic) and their distribution., Parasympathomimetic agents: SAR of Parasympathomimetic agents, Direct acting agents: Acetylcholine, Carbachol*, Bethanechol, Methacholine, Pilocarpine., Indirect acting/ Cholinesterase inhibitors (Reversible & Irreversible): Physostigmine, Neostigmine*, Pyridostigmine, Edrophonium chloride, Tacrine hydrochloride, Ambenonium chloride, Isofluorphate, Echothiophate iodide, Parathione, Malathion., Cholinesterase reactivator: Pralidoxime chloride., Cholinergic Blocking agents: SAR of cholinolytic agents, Solanaceous alkaloids and analogues: Atropine sulphate, Hyoscyamine sulphate, Scopolamine hydrobromide, Homatropine hydrobromide, Ipratropium bromide*, Synthetic cholinergic blocking agents: Tropicamide, Cyclopentolate hydrochloride, Clidinium bromide, Dicyclomine hydrochloride*, Glycopyrrolate, Methantheline bromide,, A. Sedatives and Hypnotics: Benzodiazepines: SAR of Benzodiazepines, Chlordiazepoxide, Diazepam*, Oxazepam, Chlorazepate, Lorazepam, Alprazolam, Zolpidem Barbiturtes: SAR of barbiturates, Barbital*, Phenobarbital, Mephobarbital, Amobarbital, Butabarbital, Pentobarbital, Secobarbital, Miscelleneous: Amides & imides: Glutethmide. Alcohol & their carbamate derivatives: Meprobomate, Ethchlorvynol. Aldehyde & their derivatives: Triclofos sodium, Paraldehyde., B. Antipsychotics Phenothiazeines: SAR of Phenothiazeines - Promazine hydrochloride, Chlorpromazine hydrochloride*, Triflupromazine, Thioridazine hydrochloride, Piperacetazine hydrochloride, Prochlorperazine maleate, Trifluoperazine hydrochloride., Ring Analogues of Phenothiazeines: Chlorprothixene, Thiothixene, Loxapine succinate, Clozapine., Fluro buterophenones: Haloperidol, Droperidol, Risperidone. Beta amino ketones: Molindone hydrochloride. Benzamides: Sulpieride., C. Anticonvulsants: SAR of Anticonvulsants, mechanism of anticonvulsant action, Barbiturates: Phenobarbitone, Methabarbital. Hydantoins: Phenytoin*, Mephenytoin, Ethotoin Oxazolidine diones: Trimethadione, Paramethadione Succinimides: Phensuximide, Methsuximide, Ethosuximide, Urea and monoacylureas: Phenacemide, Carbamazepine* Benzodiazepines: Clonazepam Miscellaneous: Primidone, Valproic acid , Gabapentin, Felbamate, General anesthetics: Inhalation anesthetics: Halothane*, Methoxyflurane, Enflurane, Sevoflurane, Isoflurane, Desflurane, Ultra short acting barbitutrates: Methohexital sodium*, Thiamylal sodium, Thiopental sodium., Dissociative anesthetics: Ketamine hydrochloride., Narcotic and non-narcotic analgesics Morphine and related drugs: SAR of Morphine analogues, Morphine sulphate, Codeine, Meperidine hydrochloride, Anilerdine hydrochloride, Diphenoxylate hydrochloride, Loperamide hydrochloride, Fentanyl citrate*, Methadone hydrochloride*, Propoxyphene hydrochloride, Pentazocine, Levorphanol tartarate., Narcotic antagonists: Nalorphine hydrochloride, Levallorphan tartarate, Naloxone hydrochloride., Anti-inflammatory agents: Sodium salicylate, Aspirin, Mefenamic acid*, Meclofenamate, Indomethacin, Sulindac, Tolmetin, Zomepriac, Diclofenac, Ketorolac, Ibuprofen*, Naproxen, Piroxicam, Phenacetin, Acetaminophen, Antipyrine, Phenylbutazone.
