 Basic principles of Cell injury and Adaptation: Introduction, definitions, Homeostasis, Components and Types of Feedback systems, Causes of cellular injury,Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage),Morphology of cell injury – Adaptive changes (Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia),Cell swelling, Intra cellular accumulation, Calcification, Enzyme leakage and Cell Death Acidosis &Alkalosis, Electrolyte imbalance  Basic mechanism involved in the process of inflammation and repair: Introduction, Clinical signs of inflammation, Different types of Inflammation,Mechanism of Inflammation – Alteration in vascular permeability and blood flow, migration of WBC’s, Mediators of inflammation, Basic principles of wound healing in the skin, Pathophysiology of Atherosclerosis

Cardiovascular System: Hypertension, congestive heart failure, ischemic heart disease (angina, myocardial infarction, atherosclerosis and arteriosclerosis)  Respiratory system: Asthma, Chronic obstructive airways diseases.  Renal system: Acute and chronic renal failure

 Haematological Diseases: Iron deficiency, megaloblastic anemia (Vit B12 and folic acid), sickle cell anemia, thalasemia, hereditary acquired anemia, hemophilia  Endocrine system: Diabetes, thyroid diseases, disorders of sex hormones  Nervous system: Epilepsy, Parkinson’s disease, stroke, psychiatric disorders: depression, schizophrenia and Alzheimer’s disease.  Gastrointestinal system: Peptic Ulcer

 Inflammatory bowel diseases, jaundice, hepatitis (A,B,C,D,E,F) alcoholic liver disease.  Disease of bones and joints: Rheumatoid arthritis, osteoporosis and gout  Principles of cancer: classification, etiology and pathogenesis of cancer

 Infectious diseases:Meningitis,Typhoid, Leprosy, Tuberculosis Urinary tract infections  Sexually transmitted diseases:AIDS, Syphilis, Gonorrhea