Basic principles of Cell injury and Adaptation Introduction definitions Homeostasis Components and Types of Feedback systems Causes of cellular injury Pathogenesis Cell membrane damage Mitochondrial damage Ribosome damage Nuclear damage Morphology of cell injury Adaptive changes Atrophy Hypertrophy hyperplasia Metaplasia Dysplasia Cell swelling Intra cellular accumulation Calcification Enzyme leakage and Cell Death Acidosis Alkalosis Electrolyte imbalance Basic mechanism involved in the process of inflammation and repair Introduction Clinical signs of inflammation Different types of Inflammation Mechanism of Inflammation Alteration in vascular permeability and blood flow migration of WBCs Mediators of inflammation Basic principles of wound healing in the skin Pathophysiology of Atherosclerosis

Hypertension, congestive heart failure ischemic heart disease angina myocardial infarction atherosclerosis and arteriosclerosis Respiratory system Asthma Chronic obstructive airways diseases Renal system Acute and chronic renal failure

Haematological Diseases: Iron deficiency, megaloblastic anemia (Vit B12 and folic acid), sickle cell anemia, thalasemia, hereditary acquired anemia, hemophilia  Endocrine system: Diabetes, thyroid diseases, disorders of sex hormones  Nervous system: Epilepsy, Parkinson’s disease, stroke, psychiatric disorders: depression, schizophrenia and Alzheimer’s disease.  Gastrointestinal system: Peptic Ulcer

Inflammatory bowel diseases, jaundice, hepatitis (A,B,C,D,E,F) alcoholic liver disease.  Disease of bones and joints: Rheumatoid arthritis, osteoporosis and gout  Principles of cancer: classification, etiology and pathogenesis of cancer  Diseases of bones and joints:Rheumatoid Arthritis, Osteoporosis,Gout  Principles of Cancer: Classification, etiology and pathogenesis of Cancer

Meningitis,Typhoid, Leprosy, Tuberculosis Urinary tract infections  Sexually transmitted diseases:AIDS, Syphilis, Gonorrhea