Subject Details
Dept     : B.Pharm
Sem      : 2
Regul    : 2024
Faculty : VAS
phone  : NIL
E-mail  : VAS@gmail.com
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Syllabus

UNIT
1
Basic principles of Cell injury and Adaptation:

Introduction, definitions, Homeostasis, Components and Types of Feedback systems, Causes of cellular injury,Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage),Morphology of cell injury – Adaptive changes (Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia),Cell swelling, Intra cellular accumulation, Calcification, Enzyme leakage and Cell Death Acidosis &Alkalosis,Electrolyte imbalance

UNIT
2
Cardiovascular System:

Hypertension, congestive heart failure, ischemic heart disease (angina,myocardial infarction, atherosclerosis and arteriosclerosis)  Respiratory system:Asthma, Chronic obstructive airways diseases.  Renal system:Acute and chronic renal failure

UNIT
3
Haematological Diseases:

Iron deficiency, megaloblastic anemia (Vit B12 and folic acid), sickle cell anemia, thalasemia, hereditary acquired anemia, hemophilia  Endocrine system: Diabetes, thyroid diseases, disorders of sex hormones  Nervous system: Epilepsy, Parkinson’s disease, stroke, psychiatric disorders: depression, schizophrenia and Alzheimer’s disease.  Gastrointestinal system: Peptic Ulcer

UNIT
4
Disease of bones and joints:

Rheumatoid arthritis, osteoporosis and gout  Principles of cancer: classification, etiology and pathogenesis of cancer  Diseases of bones and joints:Rheumatoid Arthritis, Osteoporosis,Gout  Principles of Cancer: Classification, etiology and pathogenesis of Cancer

UNIT
5
Infectious diseases:

Meningitis,Typhoid, Leprosy, Tuberculosis, AIDS, Syphilis, Gonorrhea

Reference Book:

4. Best, Charles Herbert 1899-1978; Taylor, Norman Burke 1885-1972; West, John B (John Burnard); Best and Taylor’s Physiological basis of medical practice; 12th ed; united states; 5. William and Wilkins, Baltimore;1991 [1990 printing]. 6. Nicki R. Colledge, Brian R. Walker, Stuart H. Ralston;Davidson’s Principles and Practice of Medicine; 21st edition; London; ELBS/Churchill Livingstone; 2010.

Text Book:

1. Vinay Kumar, Abul K. Abas, Jon C. Aster; Robbins &Cotran Pathologic Basis of Disease; South Asia edition; India; Elsevier; 2014. 2. HarshMohan; Text book of Pathology; 6th edition; India; Jaypee Publications; 2010. 3. Laurence B, Bruce C, Bjorn K. ; Goodman Gilman’s The Pharmacological Basis of Therapeutics; 12th edition; New York; McGraw-Hill; 2011.

 

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