Introduction, definitions, Homeostasis, Components and Types of Feedback systems, Causes of cellular injury,Pathogenesis (Cell membrane damage, Mitochondrial damage, Ribosome damage, Nuclear damage),Morphology of cell injury – Adaptive changes (Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia),Cell swelling, Intra cellular accumulation, Calcification, Enzyme leakage and Cell Death Acidosis &Alkalosis,Electrolyte imbalance
Hypertension, congestive heart failure, ischemic heart disease (angina,myocardial infarction, atherosclerosis and arteriosclerosis) Respiratory system:Asthma, Chronic obstructive airways diseases. Renal system:Acute and chronic renal failure
Iron deficiency, megaloblastic anemia (Vit B12 and folic acid), sickle cell anemia, thalasemia, hereditary acquired anemia, hemophilia Endocrine system: Diabetes, thyroid diseases, disorders of sex hormones Nervous system: Epilepsy, Parkinson’s disease, stroke, psychiatric disorders: depression, schizophrenia and Alzheimer’s disease. Gastrointestinal system: Peptic Ulcer
Rheumatoid arthritis, osteoporosis and gout Principles of cancer: classification, etiology and pathogenesis of cancer Diseases of bones and joints:Rheumatoid Arthritis, Osteoporosis,Gout Principles of Cancer: Classification, etiology and pathogenesis of Cancer
Meningitis,Typhoid, Leprosy, Tuberculosis, AIDS, Syphilis, Gonorrhea
Reference Book:
4. Best, Charles Herbert 1899-1978; Taylor, Norman Burke 1885-1972; West, John B (John Burnard); Best and Taylor’s Physiological basis of medical practice; 12th ed; united states; 5. William and Wilkins, Baltimore;1991 [1990 printing]. 6. Nicki R. Colledge, Brian R. Walker, Stuart H. Ralston;Davidson’s Principles and Practice of Medicine; 21st edition; London; ELBS/Churchill Livingstone; 2010.
Text Book:
1. Vinay Kumar, Abul K. Abas, Jon C. Aster; Robbins &Cotran Pathologic Basis of Disease; South Asia edition; India; Elsevier; 2014. 2. HarshMohan; Text book of Pathology; 6th edition; India; Jaypee Publications; 2010. 3. Laurence B, Bruce C, Bjorn K. ; Goodman Gilman’s The Pharmacological Basis of Therapeutics; 12th edition; New York; McGraw-Hill; 2011.