Subject Details
Dept     : B.Pharm
Sem      : 1
Regul    : PCI
Faculty : staff12
phone  : 8497908820
E-mail  : bakhatwar.m@snscphs.org
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Syllabus

UNIT
1
Historical background and development of profession of pharmacy

Historical background and development of profession of pharmacy: History of profession of Pharmacy in India in relation to pharmacy education, industry and organization, Pharmacy as a career, Pharmacopoeias: Introduction to IP, BP, USP and Extra Pharmacopoeia.  Dosage forms: Introduction to dosage forms, classification and definitions  Prescription: Definition, Parts of prescription, handling of Prescription and Prescription errors.  Posology: Definition, Factors affecting posology. Pediatric dose calculations based on age, body weight and body surface area.

UNIT
2
Pharmaceutical calculations, Powders, Liquid dosage forms

Pharmaceutical calculations: Weights and measures – Imperial & Metric system, Calculations involving percentage solutions, alligation, proof spirit and isotonic solutions based on freezing point and molecular weight.  Powders: Definition, classification, advantages and disadvantages,Simple & compound powders – official preparations, dusting powders, effervescent, efflorescent and hygroscopic powders, eutectic mixtures. Geometric dilutions.  Liquid dosage forms: Advantages and disadvantages of liquid dosage forms. Excipients used in the formulation of liquid dosage forms. Solubility enhancement techniques

UNIT
3
Monophasic, Biphasic liquids

 Monophasic liquids: Definitions and preparations of Gargles, Mouthwashes, Throat Paint, Eardrops, Nasal drops, Enemas, Syrups, Elixirs, Liniments and Lotions.  Biphasic liquids:  Suspensions: Definition, advantages and disadvantages, classifications, Preparation of suspensions; Flocculated and deflocculated suspensions & stability problems and methods to overcome.  Emulsions: Definition, classification, emulsifying agent, test for the identification of type of emulsion, Methods of preparation & stability problems, and methods to overcome.

UNIT
4
Suppositories, Pharmaceutical incompatibilities

 Suppositories: Definition, types, advantages and disadvantages, types of bases, methods of preparations. Displacement value & its calculations, evaluation of suppositories.  Pharmaceutical incompatibilities: Definition, classification, physical, chemical and therapeutic incompatibilities with examples.

UNIT
5
Semisolid dosage forms

 Semisolid dosage forms: Definitions, classification, mechanisms and factors influencing dermal penetration of drugs. Preparation of ointments, pastes, creams and gels. Excipients used in semi solid dosage forms. Evaluation of semi solid dosages forms

Reference Book:

1. H.C. Ansel et al., Pharmaceutical Dosage Form and Drug Delivery System, Lippincott Williams and Walkins, New Delhi. 2. Carter S.J., Cooper and Gunn’s-Dispensing for Pharmaceutical Students, CBS publishers, New Delhi. 3. M.E. Aulton, Pharmaceutics, The Science& Dosage Form Design, Churchill Livingstone, Edinburgh. 4. Indian pharmacopoeia. 5. British pharmacopoeia. 6. Lachmann. Theory and Practice of Industrial Pharmacy,Lea& Febiger Publisher, The University of Michigan. 7. Alfonso R. Gennaro Remington. The Science and Practice of Pharmacy, Lippincott Williams, New Delhi. 8. Carter S.J., Cooper and Gunn’s. Tutorial Pharmacy, CBS Publications, New Delhi. 9. E.A. Rawlins, Bentley’s Text Book of Pharmaceutics, English Language Book Society, Elsevier Health Sciences, USA. 10. Isaac Ghebre Sellassie: Pharmaceutical Pelletization Technology, Marcel Dekker, INC, New York. 11. Dilip M. Parikh: Handbook of Pharmaceutical Granulation Technology, Marcel Dekker, INC, New York. 12. Francoise Nieloud and Gilberte Marti-Mestres: Pharmaceutical Emulsions and Suspensions, Marcel Dekker, INC, New York.

Text Book:

M.E. Aulton, Pharmaceutics, The Science& Dosage Form Design, Churchill Livingstone, Edinburgh. Lachmann. Theory and Practice of Industrial Pharmacy,Lea& Febiger Publisher, The University of Michigan.

 

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