Subject Details
Dept     : B.Pharm
Sem      : 5
Regul    : PCI
Faculty : KALAIVANI VETRIVEL
phone  : 9894254446
E-mail  : kalaivani.v@snscphs.org
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Syllabus

UNIT
1
UNIT I - Metabolic pathways in higher plants and their determination

a) Brief study of basic metabolic pathways and formation of different secondary metabolites through these pathways- Shikimic acid pathway, Acetate pathways and Amino acid pathway. b) Study of utilization of radioactive isotopes in the investigation of Biogenetic studies.

UNIT
2
UNIT II

General introduction, composition, chemistry & chemical classes, biosources, therapeutic uses and commercial applications of following secondary metabolites: Alkaloids: Vinca, Rauwolfia, Belladonna, Opium, Phenylpropanoids and Flavonoids: Lignans, Tea, Ruta Steroids, Cardiac Glycosides & Triterpenoids: Liquorice, Dioscorea, Digitalis Volatile oils: Mentha, Clove, Cinnamon, Fennel, Coriander, Tannins: Catechu, Pterocarpus Resins: Benzoin, Guggul, Ginger, Asafoetida, Myrrh, Colophony Glycosides: Senna, Aloes, Bitter Almond Iridoids, Other terpenoids & Naphthaquinones: Gentian, Artemisia, taxus, carotenoids

UNIT
3
UNIT III

Isolation, Identification and Analysis of Phytoconstituents a) Terpenoids: Menthol, Citral, Artemisin b) Glycosides: Glycyrhetinic acid & Rutin c) Alkaloids: Atropine,Quinine,Reserpine,Caffeine d) Resins: Podophyllotoxin, Curcumin

UNIT
4
UNIT IV

Industrial production, estimation and utilization of the following phytoconstituents: Forskolin, Sennoside, Artemisinin, Diosgenin, Digoxin, Atropine, Podophyllotoxin, Caffeine, Taxol, Vincristine and Vinblastine

UNIT
5
UNIT V - Basics of Phytochemistry

Modern methods of extraction, application of latest techniques like Spectroscopy, chromatography and electrophoresis in the isolation, purification and identification of crude drugs.

Reference Book:

1. W.C.Evans, Trease and Evans Pharmacognosy, 16th edition, W.B. Sounders & Co., London, 2009. 2. Herbal drug industry by R.D. Choudhary (1996), Ist Edn, Eastern Publisher, New Delhi. 3. Essentials of Pharmacognosy, Dr.SH.Ansari, IInd edition, Birla publications, New Delhi, 2007

Text Book:

1. Mohammad Ali. Pharmacognosy and Phytochemistry, CBS Publishers & Distribution, New Delhi. 2. Text book of Pharmacognosy by C.K. Kokate, Purohit, Gokhlae (2007), 37th Edition, Nirali Prakashan, New Delhi.

 

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