
Introduction to biochemistry: Scope of biochemistry in pharmacy; Cell and its biochemical organization. Carbohydrates: Definition, classification with examples, chemical properties Monosaccharides - Structure of glucose, fructose, and galactose Disaccharides - structure of maltose, lactose, and sucrose Polysaccharides - chemical nature of starch and glycogen Qualitative tests and biological role of carbohydrates
Proteins: Definition, classification of proteins based on composition and solubility with examples Definition, classification of amino acids based on chemical nature and nutritional requirements with examples Structure of proteins (four levels of organization of protein structure) Qualitative tests and biological role of proteins and amino acids Diseases related to malnutrition of proteins. Lipids: Definition, classification with examples Structure and properties of triglycerides (oils and fats) Fatty acid classification - Based on chemical and nutritional requirements with examples Structure and functions of cholesterol in the body Lipoproteins - types, composition and functions in the body Qualitatative tests and functions of lipids.
Nucleic acids: Definition, purine and pyrimidine bases Components of nucleosides and nucleotides with examples Structure of DNA (Watson and Crick model), RNA and their functions Enzymes: Definition, properties and IUB and MB classification Factors affecting enzyme activity Mechanism of action of enzymes, Enzyme inhibitors Therapeutic and pharmaceutical importance of enzymes
Vitamins: Definition and classification with examples Sources, chemical nature, functions, coenzyme form, recommended dietary requirements, deficiency diseases of fat-and water-soluble vitamins Metabolism (Study of cycle/pathways without chemical structures) Metabolism of Carbohydrates: Glycolysis, TCA cycle and glycogen metabolism, regulation of blood glucose level. Diseases related to abnormal metabolism of Carbohydrates Metabolism of lipids: Lipolysis, β-oxidation of Fatty acid (Palmitic acid) ketogenesis and ketolysis. Diseases related to abnormal metabolism of lipids such as Ketoacidosis, Fatty liver, Hypercholesterolemia Metabolism of Amino acids (Proteins): General reactions of amino acids and its significance– Transamination, deamination, Urea cycle and decarboxylation. Diseases related to abnormal metabolism of amino acids, Disorders of ammonia metabolism, phenylketonuria, alkaptonuria and Jaundice. Biological oxidation: Electron transport chain and Oxidative phosphorylation.
Water and Electrolytes: Distribution, functions of water in the body Water turnover and balance Electrolyte composition of the body fluids, Dietary intake of electrolyte and Electrolyte balance Dehydration, causes of dehydration and oral rehydration therapy Introduction to Biotechnology Organ function tests: Functions of kidney and routinely performed tests to assess the functions of kidney and their clinical significances Functions of liver and routinely performed tests to assess the functions of liver and their clinical significances Lipid profile tests and its clinical significances Introduction to Pathology of Blood and Urine: Lymphocytes and Platelets, their role in health and disease Erythrocytes - Abnormal cells and their significance Normal and Abnormal constituents of Urine and their significance
Reference Book:
Reference Book: TAKUR PUBLICATION TEXT BOOK OF HUMAN ANATOMY AND PHYSIOLOGY
Text Book:
TAKUR PUBLICATION TEXT BOOK OF BIOCHEMISTRY AND CLINICAL PATHOLOGY Text Book: NIRALI PUBLICATION TEXT BOOK OF BIOCHEMISTRY AND CLINICAL PATHOLOGY
